DiaPep277


CAS No. : 179822-83-4

179822-83-4
Price and Availability of CAS No. : 179822-83-4
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Cat. No. : HY-105063
M.Wt: 2390.73
Formula: C106H180N28O34
Purity: >98 %
Solubility: DMSO : 12.5 mg/mL (ultrasonic);H2O : 12.5 mg/mL (ultrasonic)
Introduction of 179822-83-4 :

DiaPep277 is a 24 amino acid peptide derived from positions 437-460 in HSP60. DiaPep277 arrests the progression of β-cell destruction in NOD mice. DiaPep277 has an immune modulatory effect on diabetogenic T cells in animal models of diabetes[1][2]. In Vivo:DiaPep277 (50 μg; i.p.; single dosage) causes strong splenic T cells responses, and strong diabetogenic clones 27, C7, and C9 responses[2].

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