SDZ 220-581 (Ammonium salt)


CAS No. : 179411-94-0

179411-94-0
Price and Availability of CAS No. : 179411-94-0
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10mg $100 In-stock
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Cat. No. : HY-13059A
M.Wt: 386.77
Formula: C16H20ClN2O5P
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 179411-94-0 :

SDZ 220-581 Ammonium salt is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7[1]. IC50 & Target: pKi: 7.7 (NMDA receptor)[1] In Vivo: SDZ 220-581 (3.2-32 mg/kg; oral administration; for 24 hours; male OF-l mice) treatment dose-dependently protects mice against maximal electroshock seizures (MES). The time-course of protection by SDZ 220-581 is characterized by a rapid onset and long duration of action[1].

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