SDZ 220-581 (hydrochloride)
CAS No. : 179411-93-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $116 | In-stock |
| 10mg | $180 | In-stock |
| 25mg | $325 | In-stock |
| 50mg | $490 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
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| Cat. No. : | HY-13059B |
| M.Wt: | 406.20 |
| Formula: | C16H18Cl2NO5P |
| Purity: | >98 % |
| Solubility: | DMSO : 5 mg/mL (ultrasonic;warming);H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) |
SDZ 220-581 hydrochloride is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7[1]. IC50 & Target: pKi: 7.7 (NMDA receptor)[1] In Vivo: SDZ 220-581 (3.2-32 mg/kg; oral administration; for 24 hours; male OF-l mice) treatment dose-dependently protects mice against maximal electroshock seizures (MES). The time-course of protection by SDZ 220-581 is characterized by a rapid onset and long duration of action[1].
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