LLY-507
CAS No. : 1793053-37-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $110 | In-stock |
| 10mg | $198 | In-stock |
| 25mg | $429 | In-stock |
| 50mg | $770 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-19313 |
| M.Wt: | 574.76 |
| Formula: | C36H42N6O |
| Purity: | >98 % |
| Solubility: | DMSO : 15 mg/mL (ultrasonic;warming) |
LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2. LLY-507 potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 <15 nM. LLY-507 serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes[1].
IC50 & Target: IC50: <15 nM (SMYD2)[1]
In Vitro: LLY-507 is >100-fold selective for SMYD2 over 21 other methyltransferases including SMYD3[1].
LLY-507 binds to the substrate channel of SMYD2 and supports the selectivity of its inhibition[1].
LY-507 is able to potently inhibit the methylation of H4 peptide by SMYD2 enzyme with an IC50 of 31 nM[1].
LLY-507 (0.03-20 μM; 28 hours) inhibits SMYD2-mediated methylation of p53 Lys370 in U2OS cells, with an IC50 of 0.6 μM[1].
LLY-507 (0-20 μM; 3-7 days) inhibits the proliferation of several ESCC, HCC, and breast cancer cell lines[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- LLY-507
- Cat. No.:
- HY-19313
- Quantity:
Your information is safe with us.