SIB 1663
CAS No. : 179064-11-0
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| Cat. No. : | HY-105330 |
| M.Wt: | 204.27 |
| Formula: | C12H16N2O |
| Purity: | >98 % |
| Solubility: |
SIB 1663 is a conformationally restricted analog of nicotine. SIB-1663 selectively activatedα2β4 and α4β4 human recombinant neuronal nAChRs. SIB 1663 can increase DA and NE release. SIB 1663 can be used for the research of neurological disease[1].
In Vivo:SIB 1663 (3-30 mg/kg, s.c.) increases ipsilateral turning in rats with unilateral and increases withdrawal latencies in 6-OHDA (HY-B1081) nigrostriatal lesion rats[1].
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