Basiliximab
CAS No. : 179045-86-4
(Synonyms: CHI 621)
| Size | Price | Stock |
|---|---|---|
| 1mg | $280 | In-stock |
| 5mg | $900 | In-stock |
| 10mg | $1450 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-108852 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation[1].
IC50 & Target:Interleukin-2 receptor[1]
In Vitro: Basiliximab specifically inhibits T lymphocyte proliferation by binding to the IL-2Rα[1].
Basiliximab binds only to activated lymphocytes and macrophages/monocytes[3].
Basiliximab does not affect resting T lymphocytes that do not express IL-2Rα[3].
In Vivo: Basiliximab (CHI 621) (0.07 mg/rat; i.v.; once) decreases total placental natural killer cells in reduced uterine perfusion pressure (RUPP) rats[2].
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