| Size | Price | Stock |
|---|---|---|
| 100g | $118 | In-stock |
| 500g | $379 | In-stock |
| 1 kg | Get quote | |
| 2 kg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-17400 |
| M.Wt: | 200.17 |
| Formula: | C8H9FN2O3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 48 mg/mL;H2O : ≥ 20 mg/mL |
Tegafur (FT 207; NSC 148958) is a chemotherapeutic 5-FU prodrug used in the treatment of cancers; is a component of tegafur-uracil. IC50 & Target: Nucleoside antimetabolite/analog In Vitro: Tegafur is bioactivated to 5-FU by liver microsomal cytochrome P450 enzymes. 5-FU is subsequently converted into its active metabolites 5-fluoro-deoxyuridine-monophosphate (FdUMP) and 5-fluorouridine-triphosphate (FUTP) intracellularly; these metabolites inhibit the enzyme thymidylate synthase and intercalate into RNA, resulting in decreased thymidine synthesis, reduced DNA synthesis, disrupted RNA function, and tumor cell cytotoxicity.
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