TA-01


CAS No. : 1784751-18-3

1784751-18-3
Price and Availability of CAS No. : 1784751-18-3
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5mg $132 In-stock
10mg $220 In-stock
50mg $660 In-stock
100mg $880 In-stock
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Cat. No. : HY-100114
M.Wt: 351.32
Formula: C20H12F3N3
Purity: >98 %
Solubility: DMSO : 50 mg/mL (142.32 mM; Need ultrasonic)
Introduction of 1784751-18-3 :

TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively. TA-01 acts as a cardiogenic inhibitor. IC50 & Target: IC50: 6.4 nM (CK1ε), 6.8 nM (CK1δ), 6.7 nM (p38 MAPK)[1] In Vitro: TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively. TA-01 (5 μM) is not cytotoxic, completely inhibits cardiogenesis, but induces cardiogenesis at lower concentration[1].

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