VU590 (dihydrochloride)


CAS No. : 1783987-83-6

1783987-83-6
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Cat. No. : HY-110076
M.Wt: 561.46
Formula: C24H34Cl2N4O7
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1783987-83-6 :

VU590 dihydrochloride is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC50 of 290 nM. VU590 also inhibits Kir7.1, with an IC50 of 8 μM. VU590 dihydrochloride is not a good probe of ROMK function in the kidney[1][2]. IC50 & Target:IC50: 290 nM (Kir1.1), 8 μM (Kir7.1)[1]

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