Allopurinol (sodium)
CAS No. : 17795-21-0
| Size | Price | Stock |
|---|---|---|
| 25mg | $115 | In-stock |
| 50mg | $194 | In-stock |
| 100mg | $329 | In-stock |
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| Cat. No. : | HY-B0219A |
| M.Wt: | 159.10 |
| Formula: | C5H4N4NaO |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic;warming;heat to 60°C) |
Allopurinol sodium is a potent and orally active xanthine oxidase inhibitor with an IC50 value of 0.2-50 μM. Allopurinol sodium can be used in the research of hyperuricemia and gout. Allopurinol sodium decreases the expression of HIF-1α and HIF-2α protein. Allopurinol sodium shows anti-depressant and anti-nociception activity. Anti-leishmanial effect[1][2][3][4][5].
In Vitro: Allopurinol sodium (0, 10, 100, 1000 µg/ml; 17 h) decreases the expression of HIF-1α and HIF-2α protein in HFF and HUVEC cells[5].
Allopurinol sodium (0, 10, 100, 1000 µg/ml; 24 h) reduces angiogenesis traits of HUVEC cells[5].
In Vivo: Allopurinol sodium (39 mg/kg; p.o.; daily for 21 successive days) shows anti-depressant activity in mouse[3].
Allopurinol sodium (10-400 mg/kg; i.p.) induces anti-nociception activity in mouse[4].
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