Sauchinone
CAS No. : 177931-17-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $25 | In-stock |
| 10mg | $36 | In-stock |
| 25mg | $65 | In-stock |
| 50mg | $98 | In-stock |
| 100mg | $147 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-N0613 |
| M.Wt: | 356.37 |
| Formula: | C20H20O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 22.73 mg/mL (ultrasonic) |
Sauchinone is a diastereomeric lignan isolated from Saururus chinensis (Saururaceae). Sauchinone inhibits LPS-inducible iNOS, TNF-α and COX-2 expression through suppression of I-κBα phosphorylation and p65 nuclear translocation. Sauchinone has anti-inflammatory and antioxidant activity[1].
In Vitro: Sauchinone (1, 3, 10, 30μm; 6 hours) inhibits LPS-inducible increase in the iNOS mRNA in Raw264.7 cells[1].
Sauchinone at the concentrations of 3 and 30 μm inhibits TNF-α production in LPS-treated cells by 40 and 50%, respectively[1].
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