CBR-096-4
CAS No. : 1776931-05-5
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| Cat. No. : | HY-117485 |
| M.Wt: | 636.74 |
| Formula: | C35H40N8O4 |
| Purity: | >98 % |
| Solubility: |
CBR-096-4 is a derivative of Itraconazole (HY-17514). CBR-096-4 is an orally active antifibrotic agent with no CYP3A4 inhibitory activity. CBR-096-4 inhibits the formation of matrix-secreting activated myofibroblasts (MFBs) from multiple tissue types. CBR-096-4 inhibits Hedgehog reporter activity (GLI-LUC), VEGF-dependent growth, and αSMA-LUC reporter activity. CBR-096-4 can be used for research of fibrosis[1].
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