Efflux inhibitor-1


CAS No. : 1776055-29-8

1776055-29-8
Price and Availability of CAS No. : 1776055-29-8
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5mg $310 In-stock
10mg $495 In-stock
25mg $1040 In-stock
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Cat. No. : HY-112505
M.Wt: 479.53
Formula: C28H25N5O3
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 1776055-29-8 :

Efflux inhibitor-1 (compound 2) is a pyrazolo[1,5-a]pyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC50s of 0.45 μM and 2.17 μM, respectively[1]. IC50 & Target:IC50: 0.45 μM (ABCG2/BCRP), 2.17 μM (ABCB1)[1]

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