Ethyl glucuronide
CAS No. : 17685-04-0
| Size | Price | Stock |
|---|---|---|
| 10mg | $94 | In-stock |
| 25mg | $187 | In-stock |
| 50mg | $318 | In-stock |
| 100mg | $539 | In-stock |
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| Cat. No. : | HY-113093 |
| M.Wt: | 222.19 |
| Formula: | C8H14O7 |
| Purity: | >98 % |
| Solubility: | H2O : 125 mg/mL (ultrasonic) |
Ethyl glucuronide is an endogenous metabolite. Ethyl glucuronide is the metabolite of ethanol. Ethyl glucuronide is a biomarker for ethanol exposure that accumulates in hair and reflects the alcohol intake over a time period. Ethyl glucuronide is the agonist for TLR4[1][2]. In Vitro:Ethyl glucuronide (0-100 μM, 24 h) blocks the formation of TLR4-MD2 complex, stimulates the expression of TLR4-depenent SEAP protein in HEK-TLR4 cell[2]. In Vivo:Ethyl glucuronide (0.38 µg, intrathecal injection, single dose) reduces the tactile threshold, induces hyperalgesia in Sprague-Dawley rat models[2].
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