TAK-029
CAS No. : 176655-58-6
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|---|---|---|
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| Cat. No. : | HY-19229 |
| M.Wt: | 433.42 |
| Formula: | C19H23N5O7 |
| Purity: | >98 % |
| Solubility: |
TAK-029 is a potent GP IIb/IIIa antagonist. TAK-029 has potent antithrombotic effects with bleeding time (BT) prolongation in arterial thrombosis models. TAK-029 can be used for the research of various arterial thrombotic diseases[1].
In Vivo:在豚鼠中，TAK-029（30-100 μg/kg，静脉注射）可完全抑制 ADP 诱导的体外血小板聚集，并延长给药后的 BT[1]。
在狗中，TAK-029（30-100 μg/kg，静脉注射）可抑制 ADP 诱导的体外血小板聚集[1]。
在猴子中，TAK-029（10-30 μg/kg，静脉注射）可抑制 ADP 诱导的体外血小板聚集，并延长 BT[1]。
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