Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
CAS No. : 175724-30-8
| Size | Price | Stock |
|---|---|---|
| 100mg | $8 | In-stock |
| 250mg | $18 | In-stock |
| 1g | $40 | In-stock |
| 5g | $122 | In-stock |
| 25g | $523 | In-stock |
| 100g | $1260 | In-stock |
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| 500 g | Get quote | |
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| Cat. No. : | HY-21577 |
| M.Wt: | 505.64 |
| Formula: | C25H47NO9 |
| Purity: | >98 % |
| Solubility: | DMSO : 175 mg/mL (ultrasonic) |
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG/Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
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Inquiry Information- Product Name:
- Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
- Cat. No.:
- HY-21577
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