Methyl (E)-cinnamate


CAS No. : 1754-62-7

(Synonyms: Methyl (E)-3-phenylpropenoate)

1754-62-7
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Cat. No. : HY-W067056
M.Wt: 162.19
Formula: C10H10O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1754-62-7 :

Methyl (E)-cinnamate (EMC), a phytochemical constituent isolated from Alpinia katsumadai Hayata, is a natural flavor compound with anti-inflammatory properties. Methyl (E)-cinnamate is widely used in the food and commodity industry[1]. In Vitro: Methyl (E)-cinnamate (0~30 μM; 24 hours; MC3T3-E1 cells) significantly increases the cleaved forms of poly (ADP-ribose) polymerase (PARP) and caspase-3, while it decreases the expression levels of Survivin and Bcl-2, and significantly increases TUNEL-positive and DAPI-stained cells[1].
Methyl (E)-cinnamate (0~30 μM;7 days; MC3T3-E1 cells) suppresses the osteoblast differentiation[1].
Methyl (E)-cinnamate (1~100 μM; 24 and 48 hours; MC3T3-E1 cells) decreases cell survival and induces morphological changes. EMC decreases MAPKs signaling and cell migration[1].

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