S 18986


CAS No. : 175340-20-2

175340-20-2
Price and Availability of CAS No. : 175340-20-2
Size Price Stock
5mg $130 In-stock
10mg $210 In-stock
25mg $440 In-stock
50mg $750 In-stock
100mg $1250 In-stock
200 mg Get quote
500 mg Get quote
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Cat. No. : HY-10936
M.Wt: 224.28
Formula: C10H12N2O2S
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 175340-20-2 :

S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances rat memory in object-recognition tests[1][2]. In Vivo: S 18986 is robust memory-enhancing effects in middle-aged animals compared with aged ones. S 18986 shows antiamnesic properties in middle-aged rodents in spatial memory models [1].
S 18986 (5-50 mg/kg; i.p.) significantly increases both the induction and the maintenance of 4 and 20 bursts tetanus-evoked potentiation[1].

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