CMI977


CAS No. : 175212-04-1

(Synonyms: LDP977)

175212-04-1
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Cat. No. : HY-U00260
M.Wt: 322.33
Formula: C16H19FN2O4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 175212-04-1 :

CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor. In Vitro: CMI977 is a potent 5-lipoxygenase (5-LO) inhibitor that intervenes in the production of leukotrienes and is presently being developed for the treatment of chronic asthma. It is a single enantiomer with an all-trans (2S,5S) configuration. Of the four isomers of CMI977, the S,S isomer is found to have the best biological activity and is selected for further development.

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