CP 316311
CAS No. : 175139-41-0
| Size | Price | Stock |
|---|---|---|
| 1mg | $320 | Get quote |
| 5mg | $590 | Get quote |
| 10mg | $820 | Get quote |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-14129 |
| M.Wt: | 327.46 |
| Formula: | C21H29NO2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
CP 316311 is a potent and selective CRF1 receptor antagonist with an IC50 value of 6.8 nM. IC50 & Target: IC50: 6.8 nM (CRF1 receptor)[1] In Vitro: CP 316311 fully antagonizes CRF-stimulated adenylate cyclase activity in rat cortex and at human CRF1 receptors endogenously expressed in IMR32 cells with apparent Ki values of 7.6 and 8.5 nM, respectively[1]. In Vivo: CP 316311 (3.2 mg/kg) inhibits 125I-oCRF binding by >80% in rats. CP 316311 significantly attenuates activation of the hypothalamic?pituitary?adrenal (HPA) axis, with an MED value of 10 mg/kg, p.o. CP 316311 blocks the effects of both the exogenous and endogenous CRF in the CNS. CP 316311 blocks the effects induced by the exogeneous or endogeneous CRF in the brain in rat models[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- CP 316311
- Cat. No.:
- HY-14129
- Quantity:
Your information is safe with us.