Nitroaspirin


CAS No. : 175033-36-0

(Synonyms: NCX 4016)

175033-36-0
Price and Availability of CAS No. : 175033-36-0
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10mg $130 In-stock
25mg $222 In-stock
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100mg $474 In-stock
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Cat. No. : HY-123823
M.Wt: 331.28
Formula: C16H13NO7
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 175033-36-0 :

Nitroaspirin (NCX 4016) is a nitric oxide (NO) donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin (NCX 4016) has antithrombotic and anti-platelet properties and acts as a direct and irreversible inhibitor of COX-1. Nitroaspirin (NCX 4016) causes significant induction of cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells via down-regulation of EGFR/PI3K/STAT3 signaling and modulation of Bcl-2 family proteins[1][2][3][4].

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