N-Ac-γ-Calicheamicin-AcBut-NHS ester


CAS No. : 174885-02-0

174885-02-0
Price and Availability of CAS No. : 174885-02-0
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1mg $7200 In-stock
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Cat. No. : HY-103688
M.Wt: 1779.73
Formula: C77H99IN6O28S3
Purity: >98 %
Solubility:
Introduction of 174885-02-0 :

AcBut-N-Ac-γ-Calicheamicin is an ADC cytotoxic payload that induces cell cycle arrest and apoptosis by causing DNA double-strand breaks. AcBut-N-Ac-γ-Calicheamicin is primarily used in the synthesis of antibody-drug conjugates (ADC) and holds promise for research in the field of cancer, including acute lymphoblastic leukemia (ALL) and other hematological malignancies[1].

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