OT-7100
CAS No. : 174858-27-6
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| Cat. No. : | HY-105410 |
| M.Wt: | 384.43 |
| Formula: | C20H24N4O4 |
| Purity: | >98 % |
| Solubility: |
OT-7100 is an orally active analgesic agent. OT-7100 inhibits hyperalgesia possibly by enhancing adenosinergic neurotransmission in the dorsal horn. OT-7100 can be used for the researches of inflammation, neurological and metabolic disease such as diabetes[1]2].
In Vitro:OT-7100 (0.3-3 μM) enhances the inhibitory effect of Adenosine (HY-B0228) on the contraction of guinea pig ileum[1].
In Vivo:OT-7100 (3-30 mg/kg, p.o.) inhibits the mechanical nociceptive threshold in the injured paw in the Chung rats models[1].
OT-7100 (10-100 mg/kg, p.o., daily for 21 days) increases the nociceptive threshold in diabetic rats[2].
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