BPIQ-I
CAS No. : 174709-30-9
(Synonyms: PD 159121)
| Size | Price | Stock |
|---|---|---|
| 500μg | $218 | Get quote |
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| Cat. No. : | HY-112405 |
| M.Wt: | 354.20 |
| Formula: | C16H12BrN5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
BPIQ-I (PD 159121) is a potent and ATP-competitive EGFR tyrosine kinase inhibitor.. BPIQ-I shows anti-proliferative actively[1][2].
In Vitro: BPIQ-I (0-50 µM; 3 days) shows antiproliferative activity with EC50s of >50, 30, >50, 6.5, >50 µM for A-431, MDA-MB-468, U-87, SKOV-3, MDAMB-231 cells, respectively[1].
BPIQ-I (10 nM) blocks erbB RTKs by competing with ATP, eliminating the CO2 sensitivity[2].
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