L759633


CAS No. : 174627-50-0

174627-50-0
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Cat. No. : HY-110040
M.Wt: 384.59
Formula: C26H40O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 174627-50-0 :

L759633 is a potent and selective agonist of cannabinoid receptor (CB2) receptor, with Kis of 6.4 nM and 1043 nM for CB2 and CB1 receptors, respectively. L759633 can inhibit Forskolin-stimulated cAMP production[1][2]. In Vitro: L759633 (0.1-1000 nM) inhibits Forskolin-stimulated cyclic AMP production in CB2-transfected cells, with an EC50 of 8.1 nM[1].
L759633 inhibits Forskolin-stimulated cyclic AMP production by 48% at the concentration of 10 μM[1].

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