Tomatine
CAS No. : 17406-45-0
(Synonyms: α-Tomatine; Lycopersicin; Tomatin)
| Size | Price | Stock |
|---|---|---|
| 5mg | $60 | In-stock |
| 10mg | $100 | In-stock |
| 20mg | $160 | In-stock |
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| Cat. No. : | HY-N2166 |
| M.Wt: | 1034.19 |
| Formula: | C50H83NO21 |
| Purity: | >98 % |
| Solubility: | DMSO : 66.67 mg/mL (ultrasonic;warming;heat to 60°C) |
Tomatine is a glycoalkaloid, found in the tomato plant (Lycopersicon esculentum Mill.). Tomatine elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine also inhibits 20S proteasome activity[1]. In Vitro: Tomatine inhibits gastric carcinoma cell line (AGS), neuroblastoma cell line (SH-SY5Y) and non-small cell lung cancer cell line (A549) with IC50s of 2 µM, 1.6 µM and 1.1 µM, respectively[1].
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