NSC114792
CAS No. : 17392-79-9
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| Cat. No. : | HY-122101 |
| M.Wt: | 464.62 |
| Formula: | C26H32N4O2S |
| Purity: | >98 % |
| Solubility: |
NSC114792 is a selective JAK3 inhibitor. NSC114792 induces apoptosis. NSC114792 decreases the protein expression of p-JAK3 and p-STAT5[1].
In Vitro:NSC114792 (0, 5, 10, 20 µM; 24, 48, 72 h) inhibits BaF3-JAK3V674A and BKO84 cell viability in a time and dose-dependent manner[1].
NSC114792 (0, 5, 10, 20 µM) decreases the protein expression of p-JAK3 and p-STAT5 in a dose-dependent manner[1].
NSC114792 (0, 5, 10, 20 µM; 72 h) induces apoptosis in a dose-dependent manner in L540 cells[1].
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