Fabomotizole
CAS No. : 173352-21-1
(Synonyms: CM346)
| Size | Price | Stock |
|---|---|---|
| 5mg | $70 | In-stock |
| 10mg | $120 | In-stock |
| 25mg | $265 | In-stock |
| 50mg | $410 | In-stock |
| 100mg | $586 | In-stock |
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| Cat. No. : | HY-14895 |
| M.Wt: | 307.41 |
| Formula: | C15H21N3O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Fabomotizole (CM346) is an insecticide with anxiolytic, antianxiety, and neuroprotective activities and a substrate of p-glycoprotein. Fabomotizole inhibits the ST-segment depression induced by isoproterenol in a rat model of acute subendocardial ischemia. Fabomotizole also inhibits Giardia lamblia and has the potential to inhibit giardiasis. Fabomotizole also targets Sigma1R, NRH:quinone reductase 2 (NQO2), and MAO-A to exert anxiolytic effects[1][2][3]. In Vivo:Fabomotizole (15 mg/kg; ip; single dose) reduces ST-segment depression in anesthetized rats with endothelial dysfunction and vascular integrity in a model of methionine (3 g/kg once a day for 7 days; intragastrically)-induced endothelial dysfunction and isoproterenol (20 μg/kg/min for 5 minutes; ip)-induced acute subendocardial ischemia[1].
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