3,4-Dephostatin
CAS No. : 173043-84-0
(Synonyms: Methyl-3,4-dephostatin)
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| Cat. No. : | HY-124152 |
| M.Wt: | 168.15 |
| Formula: | C7H8N2O3 |
| Purity: | >98 % |
| Solubility: |
3,4-Dephostatin (Methyl-3,4-dephostatin) is an inhibitor of protein-tyrosine phosphatase (PTPase). 3,4-Dephostatin accelerates nerve growth factor (NGF)-induced neurite formation in PC12h cells. 3,4-Dephostatin sustains the NGF-induced tyrosine phosphorylation of proteins, most prominently that of mitogen-activated protein (MAP) kinase. 3,4-Dephostatin also prolongs epidermal growth factor (EGF)-induced tyrosine phosphorylation and activation of MAP kinase[1].
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