Propionylcarnitine
CAS No. : 17298-37-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $88 | In-stock |
| 5mg | $211 | In-stock |
| 10mg | $313 | In-stock |
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| Cat. No. : | HY-113092 |
| M.Wt: | 217.26 |
| Formula: | C10H19NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic) |
Propionylcarnitine is metabolized by carnitine acetyltransferase from propionyl-CoA. Increased propionylcarnitine is regarded as a biomarker of vitamin B12 deficiency[1][2]. In Vitro: Propionylcarnitine shows protection to beta-thalassaemic erythrocytes from oxidative stress[3]. Propionylcarnitine increases production of 14CO2 from [1-14C]pyruvate and increases the rate of formation of acetyl camitine from pyruvate[4]. Propionylcarnitine allows the endothelial cells to maintain their functionality and regulatory role on vessel activity for a longer time and decreases the formation of oxygen reactive species due to xanthine oxidase activity on hypoxanthine formed by adenine nucleotide catabolism[6]. In Vivo: Propionylcarnitine (2 mM/kg; p.o. for 4 weeks) affects plasma and urine total carnitine concentrations of mice[3].
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