Varespladib methyl
CAS No. : 172733-08-3
(Synonyms: A-002; LY333013)
| Size | Price | Stock |
|---|---|---|
| 1mg | $110 | In-stock |
| 5mg | $270 | In-stock |
| 10mg | $430 | In-stock |
| 25mg | $710 | In-stock |
| 50mg | $980 | In-stock |
| 100mg | $1350 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-17448 |
| M.Wt: | 394.42 |
| Formula: | C22H22N2O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Varespladib methyl (A-002; LY333013) is a selective inhibitor of group II secretory phospholipase A2 (PLA2). IC50 & Target: phospholipase A2 (PLA2)[1] In Vitro: Varespladib methyl (LY333013) is an orally-administered methyl ester pro-drug that is metabolized to LY315920[1]. Varespladib and its orally bioavailable prodrug, Varespladib methyl (methyl-Varespladib) shows high-level secretory PLA2 (sPLA2) inhibition at nanomolar and picomolar concentrations against 28 medically important snake venoms from six continents[2].
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