HX600
CAS No. : 172705-89-4
| Size | Price | Stock |
|---|---|---|
| 1mg | $180 | In-stock |
| 5mg | $500 | In-stock |
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| 50 mg | Get quote | |
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| Cat. No. : | HY-120875 |
| M.Wt: | 438.56 |
| Formula: | C29H30N2O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
HX600 is a synthetic agonist for RXR (Retinoid X Receptor) heterodimer complex. HX600 prevents ischemia-induced neuronal damage. HX600 has orally bioactivity[1].
In Vitro:HX600 (100-1000 μM; 24 h) is not directly neuroprotective against glutamate exposure[1].
HX600 (1 μM; 24 h) inhibits the expression of inflammatory mediators in primary microglia and prevents inflammation induced neuronal death[1].
In Vivo:HX600 (60 mg/kg; p.o.; every 24h) reduces ischemic damage and alleviates motor deficits in permanent ischemia model and Iba-1, phospho-p38 and TREM-2 immunoreactivities in the ischemic brain[1].
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