(RS)-AMPA (hydrobromide)
CAS No. : 171259-81-7
(Synonyms: (±)-AMPA (hydrobromide))
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| Cat. No. : | HY-100815C |
| M.Wt: | 267.08 |
| Formula: | C7H11BrN2O4 |
| Purity: | >98 % |
| Solubility: | H2O : 5 mg/mL (ultrasonic);DMSO : 50 mg/mL (ultrasonic) |
(RS)-AMPA hydrobromide ((±)-AMPA hydrobromide) is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2].
In Vitro:(RS)-AMPA hydrobromide induces dose-dependent depolarization in cultured fetal rat brainstem and lumbosacral spinal cord neurons by activating glutamate/quisqualate-preferring receptors[1].
(RS)-AMPA hydrobromide activates recombinant GluR-A/GluR-B AMPA receptors in cultured mammalian cells[2].
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