Ladirubicin
CAS No. : 171047-47-5
(Synonyms: PNU-159548)
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| Cat. No. : | HY-122462 |
| M.Wt: | 601.62 |
| Formula: | C29H31NO11S |
| Purity: | >98 % |
| Solubility: |
Ladirubicin (PNU-159548) is a derivative of Daunorubicin (HY-13062A). Ladirubicin exhibits DNA intercalation and DNA alkylating properties, inhibits DNA replication and transcription, causes DNA damage, and thereby exhibits antitumor efficacy. Ladirubicin exhibits the potential to penetrate the blood-brain barrier (BBB) for its high lipophilicity. Ladirubicin exhibits toxicity through suppression of bone marrow activity[1].
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