EGLU


CAS No. : 170984-72-2

(Synonyms: (2S)-α-Ethylglutamic acid; (2S)-α-EGLU)

170984-72-2
Price and Availability of CAS No. : 170984-72-2
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5mg $865 In-stock
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Cat. No. : HY-101332
M.Wt: 175.18
Formula: C7H13NO4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 170984-72-2 :

EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent[1].
In Vitro: EGLU (200 μM) selectively antagonizes (lS,3S)-ACPD-induced depressions of the monosynaptic component of the DRVRP, displaying little or no antagonist activity versus L-AP6 induced depressions or on the DRVRP alone[1].

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