TrxR1-IN-B19


CAS No. : 170950-29-5

(Synonyms: GO-Y015)

170950-29-5
Price and Availability of CAS No. : 170950-29-5
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Cat. No. : HY-120914
M.Wt: 354.40
Formula: C21H22O5
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 170950-29-5 :

TrxR1-IN-B19 (GO-Y015) (Compound B19) is a Curcumin (HY-N0005) derivative and colvalent TrxR1 inhibitor. TrxR1-IN-B19 inhibits TrxR1 enzyme activity to elevate oxidative stress, and then induce ROS-mediated ER Stress and mitochondrial dysfunction, subsequently resulting in cell cycle arrest and apoptosis[1].

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