CD2665
CAS No. : 170355-78-9
| Size | Price | Stock |
|---|---|---|
| 1mg | $50 | In-stock |
| 5mg | $120 | In-stock |
| 10mg | $200 | In-stock |
| 25mg | $420 | In-stock |
| 50mg | $695 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
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| Cat. No. : | HY-107437 |
| M.Wt: | 486.60 |
| Formula: | C31H34O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C) |
CD2665 is an orally active and selective RAR-β,γ antagonist, with Kd values of 306 nM, 110 nM for RAR-β and RAR-γ, repectively[1][3].
IC50 & Target: Ki: 110 nM (RARγ), 306 nM (RARβ)[1]
In Vitro: CD2665 (100 nM; 9 days; 3T3 cells) has significant effects on cell growth and differentiation[1].
In Vivo: CD2665 (0.6 mg/kg; Subcutaneous injection; daily, for 22 days) completely inhibits the overexpression of RARβ mRNA in the brain of alcohol treated mice[2].
CD2665 is a selective retinoid antagonist and elicits the expected maturation delay and growth plate expansion[3].
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