| Size | Price | Stock |
|---|---|---|
| 100mg | $303 | In-stock |
| 250mg | $515 | In-stock |
| 1g | $1389 | Get quote |
| 5 g | Get quote | |
| 10 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-18732 |
| M.Wt: | 188.23 |
| Formula: | C7H16N4O2 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic) |
L-NMMA (Tilarginine) is a non-selective and competitive inhibitor of nitric oxide synthase. L-NMMA inhibits three subtypes, namely nNOS, eNOS, and iNOS, and reduces NO production. L-NMMA alleviates mechanical allodynia, thermal hyperalgesia, and choroidal fibrosis. L-NMMA is applicable to research related to nociception, bone cancer pain, and myopia[1][2][3].
In Vivo:L-NMMA (50 µg; i.t.; single administration) significantly alleviates bone cancer-induced mechanical allodynia and thermal hyperalgesia in mice at 2 and 12 h post-treatment[1].
L-NMMA (20 nmol; intravitreal injection; once every other day; 2 to 4 weeks) alleviates choroidal fibrosis and delays myopia progression by inhibiting the NO signaling pathway in lens-induced myopic guinea pigs[2].
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