L-735821
CAS No. : 170228-29-2
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| Cat. No. : | HY-117174 |
| M.Wt: | 464.34 |
| Formula: | C25H19Cl2N3O2 |
| Purity: | >98 % |
| Solubility: |
L-735821 is a Potassium channel blocker and an antagonist of IKs. L-735821 inhibits the KCNQ1 channel activity with an EC50 of 0.08 μM. L-735821 can increase IKs and IKr current-voltage relations in rabbit ventricular myocytes. L-735821 fully abolishes IKs in isolated human ventricular myocytes at 100 nmol/L. L-735821 can easily enter single myocytes[1][2][3][4].
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