Acyline


CAS No. : 170157-13-8

170157-13-8
Price and Availability of CAS No. : 170157-13-8
Size Price Stock
1mg $260 In-stock
5mg $780 In-stock
10mg $1250 In-stock
50 mg Get quote
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Cat. No. : HY-16027
M.Wt: 1533.21
Formula: C80H102ClN15O14
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 170157-13-8 :

Acyline, a GnRH peptide analogue, is a GnRH antagonist that inhibits gonadotropin and testosterone (T) levels[1]. In Vivo:Acyline (50 μg, s.c., twice daily, 5 days) can result in disruption of vaginal oestrus and reduce uterine weights in female Kiss1−/−and Gpr54−/− mice, as well as a decrease in LH concentrations of female Kiss1−/− mice[1].
Acyline (50 μg, s.c., once) can reduce FSH concentrations from pre-acyline 1.51 ng/mL to post-acyline 1.27 ng/mL in male Kiss1−/− mice and from pre-acyline 2.87 ng/mL to post-acyline 1.95 ng/mL in male Gpr54−/− mice[1].

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