BMS-901715
CAS No. : 1699861-37-4
| Size | Price | Stock |
|---|---|---|
| 1mg | $500 | Get quote |
| 5mg | $1250 | Get quote |
| 10mg | $2000 | Get quote |
| 25mg | $3750 | Get quote |
| 50mg | $6000 | Get quote |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
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| Cat. No. : | HY-117453 |
| M.Wt: | 448.52 |
| Formula: | C22H28N10O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
BMS-901715 is a potent and selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with an IC50 of 3.3 nM[1][2]. IC50 & Target: IC50: 3.3 nM (Adapter protein-2 associated kinase 1 (AAK1))[2] In Vitro: Adaptor associated kinase 1 (AAK1) is a member of the Ark1/Prk1 family of serine/threonine kinases. AAK1 mRNA exists in two splice forms termed short and long. The long form predominates and is highly expressed in brain and heart. AAK1 is enriched in synaptosomal preparations and is co-localized with endocytic structures in cultured cells. AAK1 modulates clatherin coated endocytosis, a process that is important in synaptic vesicle recycling and receptor-mediated endocytosis[2].
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