ARS-1630
CAS No. : 1698055-86-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $250 | In-stock |
| 10mg | $350 | In-stock |
| 25mg | $690 | In-stock |
| 50mg | $990 | In-stock |
| 100mg | $1300 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-U00417 |
| M.Wt: | 430.84 |
| Formula: | C21H17ClF2N4O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
ARS-1630, a less active enantiomer of ARS-1620, is a novel inhibitor of mutant K-ras G12C extracted from patent WO 2015054572 A1. IC50 & Target: K-Ras G12C[1] In Vitro: KRASG12C is recently identified to be potentially druggable by allele-specific covalent targeting of Cys-12 in vicinity to an inducible allosteric switch II pocket (S-IIP). Success of this approach requires active cycling of KRASG12C between its active-GTP and inactive-GDP conformations as accessibility of the S-IIP is restricted only to the GDP-bound state. This strategy proves feasible for inhibiting mutant KRAS in vitro[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- ARS-1630
- Cat. No.:
- HY-U00417
- Quantity:
Your information is safe with us.