CGS 27023A
CAS No. : 169799-04-6
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| Cat. No. : | HY-18694 |
| M.Wt: | 429.92 |
| Formula: | C18H24ClN3O5S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
CGS 27023A is a non-peptidic and orally active MMP inhibitor with the Ki values of 43, 33, 20 and 8 nM for MMP-3, MMP-1, MMP-2 amd MMP-9, respectively. CGS 27023A prevents cartilage degradation in stromelysin-induced rabbit cartilage degradation model. CGS 27023A can be used for study of arthritis[1]. In Vivo:CGS 27023A (oral gavage, 75 µmol/kg for 10 h) prevents cartilage degradation in stromelysin-induced rabbit cartilage degradation model[1].
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