CGS-30440
CAS No. : 169319-62-4
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| Cat. No. : | HY-105319 |
| M.Wt: | 492.63 |
| Formula: | C25H36N2O6S |
| Purity: | >98 % |
| Solubility: |
CGS-30440 is a potent and orally active dual inhibitor of neutral endopeptidase (NEP) and angiotensin-converting enzyme (ACE). CGS-30440 exhibit antihypertensive and natriuretic effects. CGS-30440 also shows protective effect for chronic renal failure. CGS-30440 can be used for the research of cardiovascular disease, such as hypertension[1][2].
In Vivo:CGS-30440 (10-30 mg/kg, p.o.) decreases mean arterial pressure and left ventricular hypertrophy in hypertensive rats[1].
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