(2R,4R)-APDC
CAS No. : 169209-63-6
(Synonyms: (2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid)
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| Cat. No. : | HY-102091 |
| M.Wt: | 174.15 |
| Formula: | C6H10N2O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
(2R,4R)-APDC is a group II metabotropic glutamate receptor (mGluR) agonist. (2R,4R)-APDC affects cell proliferation by inhibiting glutamate release, enhancing motor responses produced by D1 receptor activation, or reducing brain-derived neurotrophic factor (BDNF) levels. (2R,4R)-APDC can be used in the study of epilepsy and other neurological diseases[1][2]. In Vivo:2R, 4R-APDC (1-10 nmol; ICV; daily for 14 days) decreases cell proliferation in the dentate gyrus[2].
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