SGC707
CAS No. : 1687736-54-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $46 | In-stock |
| 10mg | $72 | In-stock |
| 25mg | $150 | In-stock |
| 50mg | $248 | In-stock |
| 100mg | $495 | In-stock |
| 500mg | $1925 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
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| Cat. No. : | HY-19715 |
| M.Wt: | 298.34 |
| Formula: | C16H18N4O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
SGC707 is a potent, selective, and non-competitive PRMT3 (protein arginine methyltransferase 3) inhibitor (IC50=31 nM, Kd=53 nM). IC50 & Target:IC50: 31 nM (PRMT3)[1] In Vitro:SGC707 (0-10 μM; 6 h) binds to PRMT3 in both HEK293 and A549 cells[1]. In Vivo:SGC707 (intraperitoneal injection; 10 mg/kg; 3 times per week; 3 w) treatment reduces hepatic steatosis and plasma triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout mice[2].
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