SY-640


CAS No. : 168705-70-2

168705-70-2
Price and Availability of CAS No. : 168705-70-2
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10mg $75 In-stock
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Cat. No. : HY-106947
M.Wt: 207.23
Formula: C11H13NO3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 168705-70-2 :

SY-640 is an Acetamide derivative and has potent hepatoprotective effect. SY-640 reduces Propionibacterium acnes and Lipopolysaccharide-induced liver injury in mice[1][2]. In Vitro: SY-640 inhibits the number of liver-infiltrating cells and attenuates the increased expression of leukocyte function-associated antigen-1 on these cells[1].
In Vivo: SY-640 (Oral; 150 mg/kg; once daily for 7 days) significantly inhibits Propionibacterium acnes and Lipopolysaccharide-induced liver injury, but a single administration is without effect[1].
SY-640 (p.o.; 150 mg/kg; once daily for three days) significantly increases the liver microsomal cytochrome P-450 content and aminopyrine demethylase activity in mice. The hepatic microsomal aminopyrine demethylase activity is obviously inhibited two hours after oral administration of SY-640[2].

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