UPF-523
CAS No. : 168560-79-0
(Synonyms: AIDA)
| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
| 10mg | $240 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-101311 |
| M.Wt: | 221.21 |
| Formula: | C11H11NO4 |
| Purity: | >98 % |
| Solubility: | H2O : 16.67 mg/mL (ultrasonic;adjust pH to 10 with NaOH);DMSO : 9.52 mg/mL (ultrasonic) |
UPF-523 (AIDA), a rigid (carboxyphenyl) glycine derivative, is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a) with an IC50 of 214 μM. But UPF-523 has no effect on group II (mGlu2), group III (mGlu4) receptors or ionotropic glutamate receptors. UPF-523 has the potential for the research of the acute arthritis[1][2]. IC50 & Target: IC50: 214 μM (mGlu1a) In Vivo: UPF-523 (0.18 mg/kg; i.p.; 0.5 ml per 100 g) results in a final concentration of 100–150 mM which is below an IC50 of 214 mM[1].
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