L-163958
CAS No. : 168473-51-6
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| Cat. No. : | HY-114284 |
| M.Wt: | 730.64 |
| Formula: | C33H37BrFN5O6S |
| Purity: | >98 % |
| Solubility: |
L-163958 is an efficient, orally active, balanced angiotensin II receptor (AII receptor) antagonist. L-163958 has balanced high affinity for AT1 and AT2, with its IC50 values being 0.16, 0.12, 0.50, and 0.64 nM in rabbit aorta (AT1), rat midbrain (AT2), human adrenal gland (AT1), and human adrenal gland (AT2), respectively. L-163958 has a strong inhibitory effect on the pressor activity in rats. L-163958 can be used for the study of hypertension and related cardiovascular diseases[1].
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