Josamycin
CAS No. : 16846-24-5
(Synonyms: EN-141)
| Size | Price | Stock |
|---|---|---|
| 25mg | $50 | In-stock |
| 50mg | $80 | In-stock |
| 100mg | $130 | In-stock |
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| Cat. No. : | HY-B1920 |
| M.Wt: | 827.99 |
| Formula: | C42H69NO15 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 41.67 mg/mL;H2O : 8.33 mg/mL (ultrasonic;adjust pH to 6 with HCl) |
Josamycin (EN-141) is an orally active macrolide antibiotic exhibiting antimicrobial activity against a wide spectrum of pathogens, such as bacteria. The dissociation constant Kd from ribosome for Josamycin is 5.5 nM[1][2]. IC50 & Target:Kd: 5.5 nM (ribosome)[1] In Vivo:Blood and tissue levels of Josamycin after oral administration are 200 mg/kg to rabbits. Tissue levels are generally much higher than the blood levels, and 3 h after the administration, when the blood level is very low, the tissue levels are rather higher than those 1 h after the dose. One hour after the medication, the level in the lungs is the highest of all the tissue levels[2].
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